On 23 March 2020, Secretary-General António Guterres issued an appeal for an immediate global ceasefire to help create conditions for the delivery of lifesaving aid, reinforce diplomatic action and bring hope to places that are among the most vulnerable to the COVID-19 pandemic. As of 23 June 2020, the Secretary-General's call had received support from 179 Member States and one non-member observer State, as well as a range of regional organizations and international and local civil society actors. Some of these 179 Member States supported the call only in specific conflcit contexts or while stressing the right to continue with counter-terrorism operations. Meanwhile, a number of conflict parties responsed to the call by announcing unilateral ceasefires. This note analyses the response and discusses the opportunities and challenges presented by the Secretary-General's appeal.